Yeah I havent experienced problems with my derringer either, but I am speaking from many years of owning and working on many accelerated amigas for many people. The last machine that I had this Derringer in was actually an A2000, and I never experienced any flakiness with it whatsoever. But when I set out to build this A500+, I decided to do everything I could to ensure the highest degree of stability from the start.
I have seen many highly upgraded/accelerated AMIGA configurations that were particularly "vibration sensitive" and these have all been of the A500/A600/A1200 variety. This is due to the way that the machine is designed and the way that internal expansions have to plug into them, versus a machine such as the A2000/A3000/A4000 where almost everything is on a card, in an actual card-slot.