I think just having a second CPU to delegate and run tasks on would be very nice indeed. Something we can compile to and connect with and run software on. If there was a native way, including the use of the edge connector of the CM3, to add the ARM CPU to the system, it could provide a very nice speed bump.
Or, if you're super crazy, an A1200 trapdoor connector that had slots for two CM3 cards. One to use as a second CPU (i.e. PPC in current classic Amigas) and another to use as a virtual 68K ala FPGA or as a separate set of peripherals to harness from for the Amiga (i.e. RAM, USB, WiFi, Bluetooth, GPU, etc...).
The cards are so small that they should easily fit at an angle like most SIMMs on todays accelerators. They are also damn cheap.