If this makes it out with decent enough driver support in place and a reasonable price tag I'll probably buy one, and I'm a very casual Amiga user. I primarily want it for the ethernet, then the graphics. I don't actually use the Amigas I've acquired because I have no way to easily get new software on to them, the network should solve that. The 68040 is a nice upgrade for my 4000D/030 too. All the other features are a nice bonus.
I've thought about expanding my Amigas but the thought of trying to track down a pile of rare, old, and overpriced bits puts me off, so this is great.
The PPC is probably what I would be least interested in, but it's nice to have. There's no way I'll every pay to be an OS4 or MorphOS user as it doesn't interest me enough. This would be a great card to port AROS too though, and I'd certainly tinker with that setup.
For a good laugh what I'd really love to see is a solution like this targeting the A1000. It would be so awesome that a computer from 1985 could do all these awesome things. I'd buy that in a second.