Those big towers are a bit problematic. Yes they do have enough space vertically but often there is a metal bar running horizontally over the ATX motherboard where the PSU is located, you need to saw this off, or remove it in any other way.
The best way is to completely remove the backside and create a new back custom fit for Zorro slots and Amiga connectors and then position the PSU at the top or rotated 90-degrees.
It is a lot of hard work especially if you want it to look good afterwards.