Yes, give me an ATX mobo any day, that way it doesn't have to go in a 20 year old yellow case. :-)
If I could get a new ATX Amiga motherboard, I'd like it to be made by a reputable company, e.g. Gigabyte that make the x86 motherboards.
If the director of Gigabyte went a bit insane and decided to put some resources into a new 68k/coldfire/ppc Amiga compatible motherboard, you can be sure it wouldn't be in development for an infinite amount of time, and when it came out it wouldn't need sending back for hardware fixed! :-)