Probably not. Since there are few surplus chips around, what will you gain swapping chips from another machine. The biggest change in usability and function would come from adding peripherals: fast ram, hard drive, cd drive, sound digitizer, video capabilities, acceleration, etc. There are multiple ways to get there. 2 or 4 Megs of fast ram alone is a more profound improvement over new ECS replacements and the theoretical max of 2 megs of chip ram.
Having said that, I admit that I converted the trap door ram of all 4 of my a500s to chip ram. One A500, I put 2 megs of chip on the motherboard and only use the rtc in the trap door. Added ECS for productivity video mode - and I've never found much use for that mode. Grin.