@mooncloud
OctaMED Soundstudio uses samples like most trackers. It also supports MIDI quite well, I have have no problem controlling MIDI gear with it. Also, it does also support a type of synthesis that, IMHO isn't very good. You can make some quite interesting sounds with it, but they aren't that useful IMO. However its support for up to 64 channels, 16-bit direct to disk rendering etc more than make up for it.
MusicLine Editor is again a tracker but this one focuses more on synthesis, as I said. It uses very short waveforms that can be morphed about with envelopes, phasers, mixing, resonant filters etc into some really cool sounds. I only wish it too had some sort of direct to disk recording :-/