The new Trek film appears to be splitting the Trek universe into two (well, three including Mirror, Mirror, four if you count the changes introduced by First Contact, five if you think Voyage Home changed things, and even more if you consider the novels canon) distinct timelines: pre-JJ Trek and post-JJ Trek.
Although, Trek can't seem to make up its mind re: time travel. They've used both the classic, causal closed-loop view of time, and the quantum, multiverse view of time.
I actually think DS9 was the strongest of all the series story-wise. It certainly had the best character development of the four--including some of the most memorable guest characters (Brunt--FCA.), thanks to Jeffrey Combs--although the TOS movies really brought the Kirk-Spock-Bones relationship home.
I really enjoyed what they tried to do with Enterprise during the last season, and as always, Jeffrey Combs really shined in his guest spots (as Shran).
I think with the new film, we'll see the same {bleep}y, impetuousness we love about Kirk only without the Shatner whimsy. I can't wait to see what Karl Urban does with Bones. DeForest Kelley was awesome, and it's going to be difficult to bring the same subtle heart and selfless passion to the character. (Or maybe not. DeForest was really just playing an Old West town doc crossed with a Civil War field doc.)
EDIT:
And I thought Nemesis was about as interesting as dirt, unfortunately. I really wanted a decent Romulan story, too. Maybe that's what JJ will deliver, although there's not much left of the Romulan Empire post-Countdown.
Now that I think about it, that's what I *really* wanted from Enterprise. The energy of TNG with a DS9-style drama involving Earth, Vulcan, Romulus, and Andoria. Less let's-go-kill-the-bad-guys and more birth-of-the-Federation.
Fortunately, Battlestar Galactica has filled that gap quite nicely.