I am sorry for the isues you are having, but you should know that the Thyclacine hardware is buggy. Its chip is known to have troubles working with hubs under some circumstances.
Anyway, it is pretty usable for low speed devices (mouses, keyboards and such) if you just connect them directly without any hub, as they are not very picky on signal loss. I do not recommend the highway to be used for storage devices at all, because there is a change you might end up losing or corrupting your data.