MorphOS runs lots of AmigaOS software and games:
Myst 68k
Napalm 68k
Payback 68k
Quake 68k
TvPaint 68k
Dpaintt 5 68k (works, but but but)
Cinema 4D 68k
Photogenics 68k
WebMaker 68k
AmIRC 68k
Wookiechat 68k
iBrowse 68k
Miami/MiamiDx 68k
Genesis 68k
ClassAct 68k
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As you see, lots of AmigaOS software works. There is also nice native programs for it:
AmiNetRadio V4 PPC -music player, supports mp3, ogg, mod...
SongPlayer -music player, supports mp3 and ogg etc
MPlayer PPC -multimedia player, divx, xvid, avi, mpeg etc..
MOSnet 1.2 -native tcp/ip stack
Blender -3D making software, native
fXpaint 2.0 -great graphic program
VooDoo-X -great file archiver program. All in one
Ripper -nice music ripper
Titler -great 3D titler program
Virtua Grand Prix 2 -3D native racing game
Quake 3 -3D FPS ported game
WipeOut 2097 -3D flightracing game
QuakeMOS -Quake native
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There you have a small guide.