My Amiga(s) gets used on an almost daily basis, primarily for musick/noiz composition.
Sometimes I use the Amiga's paint programs, do a little gaming, etc.
I have a ton of video production hardware I'll be hooking up to it after I move.
Def not my only computer though, I also use MorphOS and AROS, not to mention Amithlon and a PC for all those apps we don't have. :/