To me it is more about function than speed; USB adds so much more function in terms of keyboards, mice, printers, sound (I have a dongle branded Amigo), and cameras. IF you need to boot off a USB device, I believe you can with the Deneb, but why? I just slip in a CF card in the top back of my A4000T and boot what ever; great for off-site backups of partitions. I use my CSPPC for everything else.