I have a 440ep, using the onboard gfx still, running dual 32 GB SSD's in it. Boots almost instantly. I bought it via pre-order in '08 via Amigakit and have been very pleased with it, but my usage case is very light. I just run a BBS on it, so it's got more than enough grunt for what I need.
I haven't had one single lick of problems with it, but if you're looking for a NG box to run games or do video stuff, you might want something with a bit more grunt, power wise. Plenty of people complain that the 440ep is a bit anemic power wise, but I've never had any issues with mine and they are relatively cheap ($300 or so, MB, RAM and OS) via the second hand market these days.
A lot of people love the A1 and Peg machines, but I detest IDE drives with a passion. SAM's are all SATA, thankfully. I've also had zero issues with USB at all, which can be a complaint the A1 and Peg guys have had in the past. I've literally never had a USB error, the machine has been 100% plug and play for me, USB wise, and I use USB sticks and external USB drives a *lot*.