WARNING! Long boring post ahead.
I don't know how much attention or praise this one received, but I didn't see any of it, so I will guess that it was overlooked and falls into your category. It was the first game I ever played on the Amiga and was called Millenium Return to Earth by Ian Bird & Glenn Dill, copyright Paragon Software Corp. and marketed by Microprose Software Inc.
It is a very simple, linear space strategy game of gathering resources, building equipment and various spacecraft, occasional grabbing the joystick to fight off the overbearing Martians in a 3D wireframe mode, and finally repairing the damaged Earth so it can be repopulated to win the game. The graphics are not anything spectacular, but are satisfactory, the sounds create the great atmosphere of the game and the storyline is adequate enough to (combined with the rest of the game play) keep me glued to the Amiga for hours at a time. Then I play it again and again, knowing the outcome is always going to be the same, just for the enjoyment and to try to see if I can shorten the time it takes to complete, or to lengthen the time to complete so I can create the maximum amount of resources and equipment on each colonized planet or moon. I never seem to tire of playing this simple (and maybe boring to others) game.
This game originally only worked with OS1.2, but has been released more than once by other software companies which might work on later OS versions. The later releases were called Millennium 2.2 Return to Earth. I don't think that the game play was any different, but the graphics may have been slightly altered. There is also a WHDLoad fixed version which I am pretty sure runs on all Amiga OSes.
One of my goals in life is to create a Millennium clone that has one important difference in that at start up the fixed characteristics of the planets and moons resources would be randomly switched, so the game play would be different each time you played it. If there is any other parts of the game I can make random, that will even be better. AMOS Pro, or Blitz Basic 2.1 will be my first choices to code the clone, then I plan to learn C, C++ and may then port my Basic code to C, C++ as a learning experience.
I have been told that Deuteros is very similar and I should get it, but the only time I have ever seen it was at auction and I did not win.