My thought was along the line that the FPGA projects are not fully compatible yet with the originals. And there exist lot of broken Amigas where only the motherboard is the broken part but the chips are ok. So then the idea is how feasable it would be to create a replication of the original motherboard.
Only sockets and ports need to retain their mechanical position. The rest could be optimized. Perhaps new PCB technique allow 2-layer board for the same job?
What about something like gb1000, completely new motherboards? Then include a Mediator/Prometheus like bridge and have native pci slots instead of isa... (or then bridge pci to pci-express slots too)
2 layers? please no. the inner power/ground layers are important for a few reasons.
1. signal integrity really benefits from signal trace being close to a solid power or ground plane. Not doing so makes eeverything significantly more difficult. Signal return current wants to be as close to the signal trace as possible, and solid reference planes are best for this. lose the planes, and you have to be tremendously careful about layour to avoid return current problems. yes, parts of these boards surely need this, even if a lot is still slow.
2. The first source of signal energy when a trace changes values is the power/ground plane capacitance at chip power pins. more is better. then local decoupling caps, then regional bulk caps, then the power supply.
3. power and ground routing become quite easy. having so sneak traces for them between signal traces on 2-layer would make it nightmarish.