@r.cade - Thanks for the suggestion, that sounded promising, but wasn't the case.
@mechy - Thanks. I'm starting to wonder if this isn't something with the drive/circuitry that's fairly unique and getting triggered by that game. I'm looking into other possibilities down that line. I'm sure it's not a battery corrosion issue; that baby looks/is super-clean (thankfully!)
@dan - the disk shows up as "unidentified" or something like that in workbench. Can't get to it via normal means. Since it boots on 2 other other machines, I'm less likely to think it's the disk itself. Some friends knowledgeable in the area say that the protection/loader isn't anything super-special, it's just a common custom dos.
Additional info:
I was able to, from the running system, take a dump of the KS ROM, and then use a CRC calculator (double-checked on a known good ROM from AmigaForever) to verify the dumped KS ROM, and it CRCs out fine. So, that tells me that the ROM, and everything that hooks up to it is fine.
I spent a non-zero amount of time trying to get disks working with the drives to get tools on, and roms off. I wasn't able to format a disk in the machine, copy files to it, and then dump it via my KryoFlux. Luckily, though, going the other way (using WinUAE to make an .adf with required tools, and then using KryoFlux to write it to disk) worked pretty well (the drive is still finicky). So, I'm beginning to wonder if A) I did something to the drive, or B) I did something to the drive controller circuitry:
Drive - I swapped in another drive that came with this, and got the same result. I swapped in a drive that loads that game fine on another machine, same result. So, I don't think that it's the drive itself.
Circuitry - Many other disks work OK (workbench, other games), so unless it's using some super-rare functionality, I don't see that being the issue.
Thanks for sticking with this; it's quite the puzzler!
--Robert