The Supra 500RX is very cool. I wish it had been my first expansion back in the day, my A500 (and my point of view) would have evolved a little differently.
To answer your question, the A3000 is the only Amiga (that I'm aware of) that directly uses Zip chips. The Supra uses Page Mode memory. The 3000 can use this IIRC, but, I think it is supposed to be slower than Static Column memory (preferred memory for the A3000). I think there are memory expansion boards for the 2000 that use Zips, but I've never owned one.
If you move up to 14400 series chips and max the 500RX out at 8 Megs of fast ram, some interesting possibilities open up. Namely running a RAD: device. With this you could select you favorite parts of Amiga OS and add-ons and load from floppies into RAD:. There after, soft resets are very quick. A 2 or 4 Meg RAD: can hold a lot of stuff. Grin.
