Matt_H,
if you can just drop it in, you could do that, but dont solder the clock pin to the clock signal on the motherboard (~7.1Mhz). you could then take the clock signal from where the chipset gets it, and plumb that in.
however, you then bugger up the synchronisation of the Chip / CPU taking turns with the Chip RAM so some sort of state machine would probably be in order, with a little FAST ram attached to the CPU so that you can actually make use of the extra speed.
I think, then, we're really talking some sort of accelerator I'm afraid, so you may as well build one using a 68020 at least.
however, soldering an accelerator as replacement of the 68000 would be physically more stable than the clip-over-the-CPU variety sold by Power et al.
just less convenient, and probably makes closing the 600 inconvenient !