@melott
A very good question! Do someone know this?
On my Amiga mouse, I have problems with the ball, it stops rolling. The problem is worst while playing real-time games, because of sweaty hands. The mouse mat is too slippery.
For my PC I bought a Logitech MX700, a cordless optical mouse. It's rechargable, and that's very important. It has a lot of buttons, for web-navigating and switching between windows.
This mouse is a real mouse! If I just could use it on my miggy.