I suppose that would be possible, but..
Most of the things you would have on clockport expansions and zorro extenders would probably be better suited native on the new FPGA boards...
Ethernet, USB, Video cards... All of those are planned included "features" on Natami (and FPGA Arcade, minus video although I would think some type of higher res video in their FPGA would be possible)...
Also, you use the phrase "many", but I wonder how many that really is....
Enough to justify a run of boards?
Who knows..
desiv