Well in Workbench 1024x768 even in 4 colors can be very nice with Indivision ECS/ECS modes...
Although possible without Indivision ECS, getting something to display it would be a pain.
Also a new 800x600 16 color mode is in the works. Does not use superhires modes from ECS. Again, would not be very useable without Indivision ECS even though it does not require it I believe.