If the graphics card is BVisionPPC, then yes.
If the graphics card is a Voodoo 3 in a Mediator setup, then no (Picasso 96).
If the graphics card is a Voodoo 3 in a Grex1200 setup, then yes.
If the graphics card is a Zorro II or III card connected through a Zorro A1200 busboard, then it depends (Picasso II & IV and CV643D for example can run with either software, both CGX and P96).
