My vote would be for effort on PPC os4 to cease and for a renewed back porting effort made to 68xxxx.
The reason: installed user base. I would also Persue partnerships with the guys making vampire / appolo so that cheap upgrades for amigas were available with real OS functionality to follow.
2017 is going to be interesting. After the V1200 Vampire there is the stand-alone board. Will be interesting to see what sells more volume - Vampires or Amiga Ones.