Yes. 5V cards have a single "notch" on the PCI connector. But even if you have such a card it doesn't mean it will work, as I found out.
I bought a used 9250 with single notch, which is supposed to mean a 5V card, but apparently there can also be a 3.3V requirement for some of the components, or something like that.
Bottom line if you want your card to work guaranteed you have to buy it from Elbox.
I tried to cheap out and got a used $20 card but now it just sits in a box with a bunch of other cards I don't use......sigh.