I had a ISA GUS. I actually had it following the release of that board and was a pretty early adopter.
It was great for playing MODs and had really good general MIDI, but native support was really pretty bad and the SoundBlaster compatibility did in fact use a lot of CPU, sounded strange and never worked particularly well. I ended up having two soundboards in my PC for this reason. I eventually gave up (gave it away..) on the GUS and bought an Ensoniq Soundscape.
It was good hardware, and I wanted to like it, but really not well supported at all and was overall a big headache. I'd much rather have an Ensoniq. Also consider a Roland MT32 and Soundblaster/MPU-401 compatible sound card (or Sound Canvas).
I guess GUS is well supported in the demo scene but commercial support was never that good, unless I just gave up to soon...
I had the original ISA GUS too and I remember ripping DRAM chips off my video card and installing them on the GUS to beef it up.

I can't say I ever used the SB emulation in DOS much, if at all to be honest. I used it purely for watching (listening to?) demos and coding them. Still got my old Borland Turbo Assembler boxset somewhere I think.
I even had a GUS PnP with the Interwave DSP chip in my K6-II machine in 97/98.
I got MT32 for 32 bux. I use it with DOSBOX with USB midi.
Now that is cool!
