Amiga OS4.0 on a Blizzard060/PPC @60/240Mhz, is like running your Amiga on chipmem only. Windows & icons are dreadfully slow to display on a 640x512 screen, not to mention the amount of crashes with JIT when running a lot of older Amiga Software.
Also a lot of the software for it requires a much bigger screensize (although you can slide windows on and of the screen) it's really quite annoying when a window opens up and you have to move it all over the place just to be able to use it. You can run an emulator like Frodo faster and better on the 060 side using OS3.x.
If you're going to run OS4.0 on this type of board without an RTG then expect to be quite disappointed, also Hyperion last updated it in 2007 not long after it was released and seem to have dropped support for it since. OS4.1 will not run on a classic Amiga set up.