I used to have a Cyberstorm PPC/060 processor card in my A1200T.
OctaMED runs very nicely on the 060 (with a minimum of 4MB RAM, I had at least 16MB), and was even nicer with a Toccata 16bit audio card. I never owned a Toccata but borrowed a friends for a while.. what a difference the upgrade to 16bit makes! :-D
OctaMED was coded for the 68000 series processors (up to 060s), so it wouldn't gain much performance on PPC unless the PPC was running a really good 060 emulator/JIT.
What kind of Amiga do you have? A1200?