I voted yes. The reason, x86/64 hardware is everywhere, you can get it pretty cheap and there currently is no other hardware platform that can compete with it (hoping Nvidia can make ARM an option here though in the future). I would run this on PC hardware and very rarely run Windows at home again (need to for my online game). With Amiga OS 4.x running on x86/64, you could also run Windows or Linux software on it with some additional software such as a VM.