This has been a well known design limitation of the A2091 for a long time now. It's also been a topic for discussion on many Amiga forums (including Amiga.org).
The A2091s DMAC was designed to support the 68000 bus architecture and likewise is limited to transfers within the 24 bit (16MB) address space. The C= driver (scsi.device) defaults to PIO mode if it can not perform DMA transfers. This results in much slower transfer rates.
Performance is significantly improved by using a software patch (i.e. vbak2091) or a Guru ROM to perform buffered DMA transfers above 24 bit address space.