For me I'd love a Natami in an A1000 style case. The case would also expand the number of PCI slots from one to 3-4, allowing for greater expansion. Also, a PPC CPU card for the Natami's CPU slot for those that want to run MorphOS or AOS 4 would be nice
The existing Natami MX already supports 3 PCI slots with a standard PCI riser.
As for PPC cards, that would be a project for 3rd party devs. The Natami Team focuses 100% on ensuring a future development path for the 68k architecture.