@stefcep2
Don't conflate seek times with transfer rates. For large files seek time is usually insignificant compared to the time taken to read or write the data. Here, transfer rates dominate. Now, RAM is certainly faster than hard disk here too, but what you have to consider is whether or not it matters. When streaming blue ray content, for example, existing SATA drives have ample transfer speeds, so you don't gain anything from putting it in RAM.
Conversely, for repeated access to lots of small files, seek times dominate. However, modern hard disks tend to have large caches to mitigate this and filesystems may add additional memory based caching on top of that too.