Both Amiga and 1581 disks are MFM-encoded as opposed to the 1541's GCR encoding, so it might be within the realm of possibility, actually. It's certainly not going to be supported by the drive firmware, but luckily the CBM 8-bitter drives have enough onboard RAM to allow for significant reprogrammability. There's already utilities that finagle it into reading and writing PC floppies, so I don't see why it couldn't be tweaked to support Amiga disks.