What I mean is this: If you have a tracked piece of music (all music is tracked), then each of the channels will play part of the music, one instrument at a time. The brain can easily separate the channels and recognize the instruments as independent samples, meaning it can convert a piece of music to a tracked format.
With a tracked format you can easily beat 1:2 lossless compression. A MOD recorded to WAV and compressed with, say, FLAC would be much bigger than the original MOD.
This is why I don't believe that the 1:2 ratio is dictated by nature, as bubblebobble claims. People simply don't know how to do it yet, because WAV to tracked format conversion isn't exactly easy to write, especially not without neural algorithms.