I don't really see the point. It's a nice idea in theory but for all the trouble it'll cause you, you might as well pick up a cheap, real x86 box.
What's the best next-gen Amiga(alike) setup? Something in a 1GHz G4? (I'm not too familiar with what's available, what's coming and what's vapour...) 1GHz Athlons are almost throwaway items now, and it will easily outperform any OS4 or MOS emulation on current machines.
Dunno about the PC-on-a-card solutions, although I doubt they have much in the way of 'bang-for-buck' factor.