There are some Amiga utilities to allow you to mount ADF files as a floppy to access from the Workbench, this only works if it's a stardard format AmigaDOS disk. If it's games you want to play, that won't help much because they tend not to be standard format. However, a lot of HD installers for such games store the game on an ADF image on the drive and use a custom loader, you should be able to get those working.
