@PAB
If you actively use your amiga for say 8 hours a day, the memory will get fragmented. Naturally this depends on the programs you use, but it does happen in real life (unless of course your amiga sits idle, doing nothing). For example active user (posting to a.org a lot for example) can easily get system crawling by using IBrowse for couple of hours.
If this doesn't qualify as "real life" I don't know what does.