browny:
Check that all filesystems used handle >4gig properly (that is, they have either NewStyleDevice (NSD), TrackDisk64 (TD64) or DirectScsi (DS) support. Remember that having the correct file in L: is not enough, you need to check that RDB has the correct filesystem(s) aswell.
Permit ExAll() and Unprotect are not necessarily needed, but can be enabled for FFS V44/V45, SFS and PFS3.