Hi. No, not directly as they are not pin compatible. Someone could make an adapter I think, but the closest there is would be the CSA MegaMidget Racer. Basically a 68020 running at 7.16MHz with no RAM.
Running it at 7mhz is a waste, as long as you synchronise bus access with the 7mhz clock then you can run faster. Without ram it is limited, but cache and multi cycle instructions that don't access memory will mean it would run faster.
Whenever I think of this type of thing my mind moves to fpga's. But then I'd want it connected to the agnus and denise sockets too. Then you could have 8mb of 32 bit chip ram, with better than AGA features. All you'd have left then would be paula and the cia's. But of course then you would want to improve paula too.
