Given a very limited amount of capital, say $100-200K, and ownership of the Amiga trademark, what would you do with it? (Please, no jokes, as tempting as they may be here.)
Fund an asic minimig and do a deal with QVC etc like the C64 DTV.
Then use the money and experience to produce something expandable using usb & sata & clocked faster with some modern ram (whether that is a netbook/tablet/nettop). If it's possible to build these in as a hidden bonus on the joystick models then all the better.