Give WinUAE a whirl first and see how that goes. If you already have a PC then this is not such a big investment. I'm not sure how well Catweasel PCI card is supported, but you could probably get Amiga floppy and joysticks easy enough through WinUAE. It will meet your chipset requirements, have use of the fastest hardware, and otherwise run fairly decent when you get WinUAE tweaked just right. I dink around with Amikit this way. And am investigating a much simpler 3.1/BetterWB setup this way. As far as seeing Windows or dealing with it, I have hear of ways to minimize its visual exposure.
Amithlon is very cool in a different usage regard. But maybe not the easiest path to attempt plus I wouldn't think your 68K UAE experience would be the best. I plan on soon jumping back into Amithlon with some kernel4 compatible hardware i have. And yes it will be in an old A2000 case too.
I have not personally tried the latest Aros w/ UAE. Looks good on the screen shots... This is easily tried without a big budget thanks to cheap PC hardware you probably already have.