For retro and sentimental value, there would be a lot of interested parties I suspect. At 4x the price of any comparable machine just via the fact it's a "custom case", not up my alley in the least but such offerings have appealed to some people I suppose.
I always hated the Amiga wedge boxes, but if I had the option to purchase an A4000 style or other Amiga retro case that took commodity form PC motherboards, I would gladly if it was from a reputable company. If and only if the price on said cases is comparable to the otherwise already available "generic" PC cases by guys like Thermaltake and etc. AIO/wedge PC's have always turned my stomach, even going back to the A500, heh - again, just preference. I do understand why people likethem from a space saving aspect, though - but I've been using a KVM for 10 years, so space isn't much of a concern.
I have never been a fan of buying prebuilt pc's, regardless of what case they come in, mainly due to the fact putting together a custom PC via components is dead simple even for a first timer these days. Same reason I had no interest in the X1000 since you cannot just buy the motherboard/OS package sans case, but building my own rigs is mainly preference and it's infinitely cheaper than buying prebuilt more enthusiast grade pc's. If you can operate a TV remote, you can assemble a PC from parts.
Last prebuilt desktop PC I bought was in the late 90's, tbh - and I'd never buy one again for personal use, so the prebuilt fully built system ideal doesn't appeal to me.