That depends on how far you want to spend money to it :-)
For example, your machine has got 1 Mb Chip memory standard and can be expanded by a A500+ Ram expansion to 2 Mb. A dream to play A500 floppy games, really !!
But if you really wanna get serious then you can do the following stuff. Get a pc-mouse-adapter so you can connect almost any pc mouse. Search for a scsi harddrive expansion that you can plug in the port on the left side of your A500+. In such an expansion you can plug up to 8 Mb memory to bring your A500+ to the maximum of 9 Mb, that´s the most you can get by using the original processor. You can also upgrade the whole system by adding a Viper 520 which gives you a 68020 processor and a fully 3,5" IDE port that allows you to add any harddrive and any cdrom ... want more ? There is loads more to add !!!