ram speed is a concern. if the system normally is running with no wait states with 70 nanosecond ram and you speed it up it will have to wait for the ram thereby nullifying the speedup. 50 nanosecond ram may allow it to run faster.
if the support chips and cpu can stand 50mhz and the sysem doesnt have 60 or even 50 nsec ram get it it will probably give you another 5 to 10% in speed.