X86 is the only cheap AND incredibly powerful CPU now. Everything else is either a toy in performance or grossly overpriced alternative really.
What we need is either a port of OS4 to x86 64 and 32bit flavour with multithreading and multiprocessing Kernal. Or Amithlon+++ with the same.
On top of that MANY improvements for modern OS demands.
What is NOT required is support for a million gpu/audio/motherboard combos. Pick a locked hardware reference for one high end x86 setup and one medium spec desktop and ditto for laptop. Stick them in a bespoke case. Works well for Apple because you sell it on no virus/windows rot(registry bloat)/responsiveness etc 
While I can concur I don't want another pc-clone with a different OS under the hood. A better idea would be to make an Amiga clone using modern hardware with an x86 CPU and several off the shelf chips to make it function like an Amiga, then add a 68k CPU for emulation purposes.
