IMHO I love that people like SpeedGeek and Cosmos are taking on these "micro optimizations" of old Amiga code. I know other people's mileage may vary, but I'm running a ton of their patches on my A2000, and sitting right next to a 2000MHz PC running the latest version of Lubuntu, my 33MHz Amiga still feels like it flies. 
You can make them faster turning off things like pop up info and prefetch.
You could be limited by bloated programs.
