I own both the F-100 and F-200 and have been messing with them for a couple of years now. I've haven't used an Amiga emulator on them but they run MAME and others very well. The NeoGeo emu rocks but is very similar to the MAME emu for it.
I can tell you this, it is very easy to use and get up and running in like 10 min. As you know the following is huge and GP2 File archive is great.
http://dl.openhandhelds.org/cgi-bin/gp2x.cgi?0,0,0,0,5,1215I am waiting on the Pandora to get it's butt in gear, it will be a powerhouse compaired to any other Linux based handheld but they are dragging feet, I pre-ordered mine over 8 months ago:(
Scott