Not long ago I was facing the same dilemma and somehow was
forced to go the AMOS way. I was (and still am) into a text adventure project which will eventually have a spanish version, and Blitz2 editor happened not to support spanish characters. Amiblitz solved that, but It is oriented to expanded high level machines with the latest KS and WB, and I wanted my stuff to work at least in a 1 MB A500. So mine was an easy choice!
Once into AMOS It's got its limitations. No OS friendly, no official AGA support... But in other aspects it manages to make your programming-newbie life easier. If your emphasis is in the "do the least" bit I recommend it. If you're worried about "quality" then remember quality not only depends on which language you're using but also on having resources like access to skilled graphics and music authors (without that your game will look amateurish no matter what you wrote it with!)
Are you planning to make a game? Tell us about it!
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