YEah you can do that as long as you can figure a way to cram the keyboard and top case half back on.
A friend ran a BBS for a while with an ICD AD-IDE hardisk controller in the 68000 socket, and then an Mtec 020/14mhz plugged on top of that.. It worked, but he had to "space" the keyboard up about 2 inches, and was unable to put the top case half back on the machine.
