Assuming you set your scsi cdrom ID properly it should work without problems. Ensure you set the jumper for SCSI ID. Any issues you may experience may be due to old firmware (6.6, 6.1 etc). I can offer you firmware upgrade to 7.0 - email for details.
The version 7 ROM fixes the following bugs in the 6.6 ROM
- >1GB HD support
- DMA reselection bug fixed
- disconnect/reconnect performance improved a lot
- Sync messages are handled
- Error handling improved
- Sync problems with Seagate/Syquest fixed
- Removable media recognition fixed
- Slow boot jumper now does a 15 second wait plus 300ms scan :-D
