I have used a product called "System Suite" by V-com since 1998. It has a very good registry cleaner among other tools. It uses the Trend micro anti-virus definitions, but not the trend virus cleaner. It also has a very good system diagnostic tool that reports in plain language. It takes up virtually no system resources on a day to day basis, but when is cleaning, it does bog the system down. I can safely say, I have never got a virus running it in the past 7 years. But, that just goes to say nothing, as I am pretty safe with my surfing habits. I like it because it scans my downloads and torrents before they are ever completed and will let you know right away if they are infected. There is a free 15 day trial on v-com's website, enough to get you started, just remember you can't have 2 anti-virus programs running at the same time or shouldn't do to conflicts.